Single-cell sequencing reveals the reproductive variations between primiparous and multiparous Hu ewes.

ABSTRACT:

Background

In the modern sheep production systems, the reproductive performance of ewes determines the economic profitability of farming. Revealing the genetic mechanisms underlying differences in the litter size is important for the selection and breeding of highly prolific ewes. Hu sheep, a high-quality Chinese sheep breed, is known for its high fecundity and is often used as a model to study prolificacy traits. In the current study, animals were divided into two groups according to their delivery rates in three consecutive lambing seasons (namely, the high and low reproductive groups with ≥ 3 lambs and one lamb per season, n = 3, respectively). The ewes were slaughtered within 12 h of estrus, and unilateral ovarian tissues were collected and analyzed by 10× Genomics single-cell

SUBMITTER: Ge T 

PROVIDER: S-EPMC10644470 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature