Vancomycin resistant enterococcus risk factors for hospital colonization in hematological patients: a matched case-control study.

ABSTRACT:

Background

Vancomycin-resistant enterococcus (VRE) was the fastest growing pathogen in Europe in 2022 (+ 21%) but its clinical relevance is still unclear. We aim to identify risk factors for acquired VRE rectal colonization in hematological patients and evaluate the clinical impact of VRE colonization on subsequent infection, and 30- and 90-day overall mortality rates, compared to a matched control group.

Methods

A retrospective, single center, case-control matched study (ratio 1:1) was conducted in a hematological department from January 2017 to December 2020. Case patients with nosocomial isolation of VRE from rectal swab screening (≥ 48 h) were matched to controls by age, sex, ethnicity, and hematologic disease. Univariate and multivariate logistic regression compared ris

SUBMITTER: Meschiari M 

PROVIDER: S-EPMC10644555 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature