Comparison of the 12-month impact of COVID-19 and SARS on physiological capacity and health-related quality of life.

ABSTRACT:

Background

Little is known about the differences in medium to long-term recovery on spirometry, 6-minute walking distance (6MWD) and health-related quality of life (HRQoL) between COVID-19 and SARS.

Methods

We performed a 12-month prospective study on COVID-19 survivors. The changes in dynamic lung volumes at spirometry (%predicted FEV₁, %predicted FVC), 6MWD and HRQoL at 1-3, 6 to 12 months were compared against a historical cohort of SARS survivors using the same study protocol. The residual radiological changes in HRCT in COVID-19 survivors were correlated with their functional capacity.

Results

108 COVID-19 survivors of various disease severity (asymptomatic 2.9%, mild 33.3%, moderate 47.2%, severe 8.3%, critical 8.3%) were recruited. When compared with

SUBMITTER: Chan KKP 

PROVIDER: S-EPMC10644631 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature