Next generation sequencing to identify iron status and individualise blood donors' experience.

ABSTRACT:

Background

Young adults form the majority of first-time blood donors to Australian Red Cross Lifeblood. However, these donors pose unique challenges for donor safety. Young blood donors, who are still undergoing neurological and physical development, have been found to have lower iron stores, and have higher risks of iron deficiency anaemia when compared to older adults and non-donors. Identifying young donors with higher iron stores may improve donor health and experience, increase donor retention, and reduce the burden on product donation. In addition, these measures could be used to individualise donation frequency.

Materials and methods

Stored DNA samples from young male donors (18-25 years; No.=47) were sequenced using a custom panel of genes identified in the literatur

SUBMITTER: Jacko G 

PROVIDER: S-EPMC10645347 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature