Managing the Skin Microbiome as a New Bacteriotherapy for Inflammatory Atopic Dermatitis.

ABSTRACT: The microbiome, comprising various bacteria, assumes a significant role in the immune system's maturation and maintaining bodily homeostasis. Alterations in the microbial composition can contribute to the initiation and progression of inflammation. Recent studies reveal that changes in microbial composition and function, known as dysbiosis in the skin and gut, have been associated with altered immunological responses and skin barrier disruption. These changes are implicated in the development of several skin diseases, such as atopic dermatitis (AD). This review examines research demonstrating the potential of microbiome repair as a therapeutic approach to reduce the effect of inflammatory processes in the skin during atopic dermatitis. This way, corticosteroids in atopic dermatitis therapy

SUBMITTER: Dewi DAR 

PROVIDER: S-EPMC10645580 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature