Optimization of oil yield of Pelargonium graveolens L'Her using Box-Behnken design in relation to its antimicrobial activity and in silico study.

ABSTRACT: Pelargonium graveolens L'Hér is an important species of genus Pelargonium with an economic value. The unique rose scent of its oil is used in perfume and cosmetic industry. The oil is characterized by the presence of citronellol, geraniol and rose oxide. Fresh aerial parts of P. graveolens at GC-MS analysis of four seasons revealed that autumn constituted the highest yield of the oil. For the first time, optimization of the yield of extracted oil of P. graveolens was performed employing 3-level Box-Behnken design using 3-factors. The GC-MS analysis of the essential oil was performed for the 17-runs. The optimized extraction of the oil was performed employing numerical optimization and studied for antimicrobial, Minimum Inhibitory Concentration (MIC) and biofilm inhibitory activities. The 3

SUBMITTER: Wafa SSAE 

PROVIDER: S-EPMC10645939 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature