Distinguishable Colorimetric Biosensor for Diagnosis of Prostate Cancer Bone Metastases.

ABSTRACT: Castration-resistant prostate cancer (PCa) causes severe bone metastasis (BM), which significantly increases mortality in men with PCa. Imaging tests and radiometric scanning require long analysis times, expensive equipment, specialized personnel, and a slow turnaround. New visualization technologies are expected to solve the above problems. Nonetheless, existing visualization techniques barely meet the urgency for precise diagnosis because the human eyes cannot recognize and capture even slight variations in visual information. By using dye differentiated superposition enhancement colorimetric biosensors, an effective method to diagnose prostate cancer bone metastases (PCa-BM) with excellent accuracy for naked-eye quantitative detection of alkaline phosphatase (ALP) is developed. The biom

SUBMITTER: Li M 

PROVIDER: S-EPMC10646272 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature