Simple demographic, laboratory and chest radiograph variables can identify COVID-19 patients with pulmonary thromboembolism: a retrospective multicentre United Kingdom study.

ABSTRACT:

Objectives

To (1) identify discriminatory demographic, laboratory and initial CXR findings; (2) explore correlation between D-dimer and radiographic severity scores; and (3) assess accuracy of published D-dimer thresholds to identify pulmonary thromboembolism (PTE) in COVID-19 patients.

Methods

Retrospective study including all COVID-19 patients admitted from 1st to 30th April 2020 meeting inclusion criteria from 25 (blinded) hospitals. Demographics, blood results, CXR and CTPA findings were compared between positive and negative PTE cohorts using uni- and multivariable logistic regression. Published D-dimer cut-offs were applied.

Results

389 patients were included [median age 63; 237 males], of which 26.2% had a PTE. Significant univariable discriminators for PTE wer

SUBMITTER: Gangi A 

PROVIDER: S-EPMC10646650 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature