Intravenous thrombolysis upon flow restoration improves outcome in endovascular thrombectomy.

ABSTRACT:

Background

We hypothesized that ongoing IV thrombolysis (IVT) at flow restoration in patients with acute ischemic stroke (AIS) treated with IVT and endovascular thrombectomy (ET) is associated with improved outcome.

Methods

We included patients with IVT and successful recanalization (modified Thrombolysis in Cerebral Infarction score ≥2b) after ET from an observational multicenter cohort, the German Stroke Registry - Endovascular Treatment trial. Procedural characteristics and functional outcome at discharge and 90 days were compared between patients with and without ongoing IVT at flow restoration. To determine associations with functional outcome, adjusted ORs were calculated using ordinal multivariable logistic regression models adjusted for potential baseline confounder

SUBMITTER: Weller JM 

PROVIDER: S-EPMC10646906 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature