Crusted scabies in a rabbit model: a severe skin disease or more?

ABSTRACT:

Background

Around 200-300 million people are estimated to be affected by scabies annually worldwide. However, the mechanisms by which this disease may affect the general condition of the host are not entirely clear. The aim of the present study was to evaluate the systemic changes that may accompany crusted scabies in both treated and non-treated experimental animals.

Methods

Male New Zealand rabbits were infected with Sarcoptes scabiei var. cuniculi and divided into the following three groups: control, ivermectin-treated, and fluralaner-treated. Several methods were used to evaluate the systemic changes, including histopathological examination of the liver, kidney, heart, and spleen, as well as the measurement of serum biochemical parameters and immunological parameters.

SUBMITTER: Sharaf MS 

PROVIDER: S-EPMC10647032 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature