ABO and Rh blood groups and risk of infection: systematic review and meta-analysis.

ABSTRACT:

Background

Persons with non-O and Rh-positive blood types are purported to be more susceptible to infection, including SARS-CoV-2, but there remains uncertainty about the degree to which this is so for both non-viral and viral infections.

Methods

We systematically reviewed Embase and PubMed from January 1^st 1960 to May 31^st 2022. English-language publications were selected that separately investigated the relation between ABO and/or Rh blood group and risk of SARS-CoV-2 and non-SARS-CoV-2 infection. Pooled odds ratios (OR_p) and 95% confidence intervals (CI) were then generated for each.

Results

Non-O blood groups had a higher OR_p for SARS-CoV-2 than O blood groups, both within 22 case-control studies (2.13, 95% CI 1.49- 3.04

SUBMITTER: Butler EA 

PROVIDER: S-EPMC10647048 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature