The transcriptional activator XlnR regulates both xylanolytic and endoglucanase gene expression in Aspergillus niger.

ABSTRACT: The expression of genes encoding enzymes involved in xylan degradation and two endoglucanases involved in cellulose degradation was studied at the mRNA level in the filamentous fungus Aspergillus niger. A strain with a loss-of-function mutation in the xlnR gene encoding the transcriptional activator XlnR and a strain with multiple copies of this gene were investigated in order to define which genes are controlled by XlnR. The data presented in this paper show that the transcriptional activator XlnR regulates the transcription of the xlnB, xlnC, and xlnD genes encoding the main xylanolytic enzymes (endoxylanases B and C and beta-xylosidase, respectively). Also, the transcription of the genes encoding the accessory enzymes involved in xylan degradation, including alpha-glucuronidase A, acety

SUBMITTER: van Peij NN 

PROVIDER: S-EPMC106473 | biostudies-literature | 1998 Oct

REPOSITORIES: biostudies-literature