Aptamers as Potential Therapeutic Tools for Ovarian Cancer: Advancements and Challenges.

ABSTRACT: Ovarian cancer (OC) is the most common lethal gynecologic cause of death in women worldwide, with a high mortality rate and increasing incidence. Despite advancements in the treatment, most OC patients still die from their disease due to late-stage diagnosis, the lack of effective diagnostic methods, and relapses. Aptamers, synthetic, short single-stranded oligonucleotides, have emerged as promising anticancer therapeutics. Their ability to selectively bind to target molecules, including cancer-related proteins and receptors, has revolutionized drug discovery and biomarker identification. Aptamers offer unique insights into the molecular pathways involved in cancer development and progression. Moreover, they show immense potential as drug delivery systems, enabling targeted delivery of the

SUBMITTER: Szymanowski W 

PROVIDER: S-EPMC10647731 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature