A Severity Comparison between Italian and Israeli Rett Syndrome Cohorts.

ABSTRACT: Rett syndrome (RTT) is a neurodevelopmental disorder marked by profound cognitive, communication, and motor impairments. Despite identified genotype/phenotype connections, the extent of clinical severity varies even among individuals sharing the same genetic mutation. Diverse sociocultural environments, such as the level of inclusivity of the scholar system, the time spent with family, and the intensity of the rehabilitative intervention provided, might influence their development diversely. This study examines the severity of RTT in people in Italy and Israel, countries with distinct contradictory approaches to caring for those with intricate disabilities, across two age groups. Data from 136 Italian and 59 Israeli girls and women with RTT were assessed and divided into two age categories

SUBMITTER: Romano A 

PROVIDER: S-EPMC10648171 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature