The Neurotoxic Effect of Environmental Temperature Variation in Adult Zebrafish (Danio rerio).

ABSTRACT: Neurotoxicity consists of the altered functionality of the nervous system caused by exposure to chemical agents or altered chemical-physical parameters. The neurotoxic effect can be evaluated from the molecular to the behavioural level. The zebrafish Danio rerio is a model organism used in many research fields, including ecotoxicology and neurotoxicology. Recent studies by our research group have demonstrated that the exposure of adult zebrafish to low (18 °C) or high (34 °C) temperatures alters their brain proteome and fish behaviour compared to control (26 °C). These results showed that thermal variation alters the functionality of the nervous system, suggesting a temperature-induced neurotoxic effect. To demonstrate that temperature variation can be counted among the factors that

SUBMITTER: Maffioli E 

PROVIDER: S-EPMC10648238 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature