Association of admission cortisol levels with outcomes and treatment response in patients at nutritional risk : A secondary analysis of a randomized clinical trial.

ABSTRACT:

Introduction

Cortisol is a metabolically active stress hormone that may play a role in the pathogenesis of malnutrition. We studied the association between admission cortisol levels and nutritional parameters, disease severity, and response to nutritional support among medical inpatients at nutritional risk.

Methods

Admission cortisol was measured in a subset of 764 patients participating in the Effect of Early Nutritional Support on Frailty, Functional Outcomes, and Recovery of Malnourished Medical Inpatients Trial (EFFORT), a multicentre, randomized-controlled trial that compared individualized nutritional support with usual nutritional care.

Results

Overall, mean cortisol levels were 570 (± 293) nmol/L and significantly higher in patients with high nutritional risk

SUBMITTER: Durmisi M 

PROVIDER: S-EPMC10648344 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature