Plasmid-encoded VCC-1 β-lactamase in a clinical isolate of Aeromonas caviae.

ABSTRACT: Vibrio cholerae carbapenemase (VCC-1) is a chromosomal encoded class A carbapenemase thus far reported in environmental Vibrio cholerae isolates. Here, we report the first isolation of a bla_VCC-1 -carrying Aeromonas caviae from a clinical sample in Israel. The isolate was resistant to all β-lactam agents, including carbapenems. The bla_VCC-1 was located on a large plasmid. GC content suggests that the origin of the bla_VCC-1 gene is neither Aeromonas nor Vibrio spp. but an unknown progenitor.

SUBMITTER: Bychenko Banyas D 

PROVIDER: S-EPMC10649018 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature