Living Donors' Age Modifies the Impact of Pre-Donation Estimated Glomerular Filtration Rate on Graft Survival.

ABSTRACT:

Background

The global scarcity of organs for kidney transplants (KTs) has led to the increased acceptance of living donors (LDs) with minor abnormalities to increase the donor pool.. We sought to evaluate the effects of some of these LDs' clinical characteristics (older age, borderline renal function, hypertension, dyslipidemia, smoking, and obesity) on graft outcomes.

Methods

We studied 352 recipients of LDKTs (1998-2020). Firstly, considering the recipients and KT variables, we identified relevant predictors of overall and censored graft failure (GF). Then, adjusting for these predictors, we explored LD variables as predictors of overall and censored GF in a multivariable Cox model.

Results

The recipients from LD with higher eGFR (≥90 mL/min/1.73 m²) had

SUBMITTER: Almeida M 

PROVIDER: S-EPMC10649187 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature