An Evaluation to Establish the Acceptable Serum Triglyceride Levels in Neonates Receiving Intravenous Fat Emulsion Infusion in a Multicenter Retrospective Study.

ABSTRACT:

Objective

This study aimed to establish neonatal serum triglyceride (TG) level reference ranges during lipid infusion and correlate peak TG with neonatal outcomes.

Study design

This is a retrospective review of 356 neonates with 696 TG measures obtained in four neonatal intensive care units between 2015 and 2017. TG was evaluated collectively to establish a reference range and a threshold limit. To analyze the effects of a higher TG threshold, neonates were categorized by their peak TG: <180 (TG^<180), 180 to 400 (TG^180-400), and > 400 mg/dL (TG^>400). Univariable and multivariable regression models were constructed to compare peak TG to patient characteristic and clinical outcomes.

Results

The frequency of TG > 400 mg/dL was 5% and foun

SUBMITTER: Chan B 

PROVIDER: S-EPMC10649198 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature