Ontology highlight
ABSTRACT:
SUBMITTER: Alvarez D
PROVIDER: S-EPMC10649644 | biostudies-literature | 2023 Nov
REPOSITORIES: biostudies-literature
Álvarez Daniela D Ortiz Macarena M Valdebenito Gabriel G Crisosto Nicolás N Echiburú Bárbara B Valenzuela Rodrigo R Espinosa Alejandra A Maliqueo Manuel M
Nutrients 20231106 21
A high-fat diet (HFD) during pregnancy promotes fat accumulation and reduces docosahexaenoic acid (DHA) levels in the liver of the offspring at postnatal ages, which can depend on fetal sex. However, the prenatal mechanisms behind these associations are still unclear. Thus, we analyzed if an HFD alters DHA content and the expression of molecules related to fatty acid (FA) metabolism in the fetal liver. Female C57BL/6 mice were fed a control diet or HFD for 4-6 weeks before pregnancy until the ge ...[more]