Association between Gut Microbiota and Breast Cancer: Diet as a Potential Modulating Factor.

ABSTRACT: Breast cancer (BCa) has many well-known risk factors, including age, genetics, lifestyle, and diet; however, the influence of the gut microbiome on BCa remains an emerging area of investigation. This study explores the connection between the gut microbiome, dietary habits, and BCa risk. We enrolled newly diagnosed BCa patients and age-matched cancer-free controls in a case-control study. Comprehensive patient data was collected, including dietary habits assessed through the National Cancer Institute Diet History Questionnaire (DHQ). 16S rRNA amplicon sequencing was used to analyze gut microbiome composition and assess alpha and beta diversity. Microbiome analysis revealed differences in the gut microbiome composition between cases and controls, with reduced microbial diversity in BCa patie

SUBMITTER: Altinok Dindar D 

PROVIDER: S-EPMC10649662 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature