Methylliberine Ingestion Improves Various Indices of Affect but Not Cognitive Function in Healthy Men and Women.

ABSTRACT: This study assessed the acute effects of oral methylliberine (Dynamine^TM) supplementation on cognitive function and indices of well-being. This was a double-blind, randomized, within-subject crossover trial. In total, 25 healthy men and women (33.5 ± 10.7 yr, 172.7 ± 8.6 cm, 73.3 ± 11.0 kg) underwent pretesting before ingesting methylliberine (100 mg) or a placebo (PLA) for 3 days. On the fourth day, the participants were tested before their fourth dose (baseline) and every hour post-ingestion for 3 h. After a one-week washout period, the participants repeated testing with the alternate investigational product. The testing battery consisted of vitals, Stroop test, Trail Making Test-B, and visual analog scales that assessed various indices of well-being. Mixed factorial ANOVAs wi

SUBMITTER: La Monica MB 

PROVIDER: S-EPMC10650428 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature