Oral Zinc-Rich Oyster Supplementation Corrects Anemia in Rats.

ABSTRACT: This study investigates the impact of various zinc supplementation methods on anemia in rats induced by phenylhydrazine (PHZ) and in 5/6-nephrectomized anemic rats. We compare oral zinc sulfate (ZnSO₄) supplementation, oyster Crassostrea gigas supplementation, and hard clam Meretrix lusoria supplementation on red blood cell (RBC) levels. Oral zinc-rich oyster supplementation (2.70 mg Zn (30 g oyster)/day/rat) effectively corrects anemia in both experimental groups. Rats orally fed oysters for four days exhibit similar effectiveness as those receiving a single ZnSO₄ injection (0.95 mg Zn (4.18 mg ZnSO₄⋅7H₂O)/rat). In contrast, oral ZnSO₄ supplementation (2.70 mg Zn (11.88 mg ZnSO₄⋅7H₂O)/day/rat) does

SUBMITTER: Chen YH 

PROVIDER: S-EPMC10650441 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature