Fluoroquinolone-Based Organic Salts (GUMBOS) with Antibacterial Potential.

ABSTRACT: Antimicrobial resistance is a silent pandemic considered a public health concern worldwide. Strategic therapies are needed to replace antibacterials that are now ineffective. One approach entails the use of well-known antibacterials along with adjuvants that possess non-antibiotic properties but can extend the lifespan and enhance the effectiveness of the treatment, while also improving the suppression of resistance. In this regard, a group of uniform materials based on organic salts (GUMBOS) presents an alternative to this problem allowing the combination of antibacterials with adjuvants. Fluoroquinolones are a family of antibacterials used to treat respiratory and urinary tract infections with broad-spectrum activity. Ciprofloxacin and moxifloxacin-based GUMBOS were synthesized via anion

SUBMITTER: Costa FMS 

PROVIDER: S-EPMC10650486 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature