Characterizing prenatal maternal distress with unique prenatal cortisol trajectories.

ABSTRACT:

Objective

It is widely assumed that glucocorticoids represent a primary mechanism through which exposure to adversity and maternal psychological distress shape prenatal developmental trajectories of both mother and fetus. However, despite repeated investigations and the fact that prenatal cortisol has been reliably linked to developmental outcomes, the empirical evidence supporting an association between prenatal cortisol and maternal distress is scarce. In this study, a novel approach to assessing links between maternal prenatal psychological distress and gestational cortisol profiles, general growth mixture modeling (GGMM), was applied.

Method

Measures of pregnancy anxiety, perceived stress, and state anxiety and depressive symptoms as well as plasma samples (for determina

SUBMITTER: Peterson GF 

PROVIDER: S-EPMC10650951 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature