The Azotobacter vinelandii AlgU regulon during vegetative growth and encysting conditions: A proteomic approach.

ABSTRACT: In the Pseduomonadacea family, the extracytoplasmic function sigma factor AlgU is crucial to withstand adverse conditions. Azotobacter vinelandii, a closed relative of Pseudomonas aeruginosa, has been a model for cellular differentiation in Gram-negative bacteria since it forms desiccation-resistant cysts. Previous work demonstrated the essential role of AlgU to withstand oxidative stress and on A. vinelandii differentiation, particularly for the positive control of alginate production. In this study, the AlgU regulon was dissected by a proteomic approach under vegetative growing conditions and upon encystment induction. Our results revealed several molecular targets that explained the requirement of this sigma factor during oxidative stress and extended its role in alginate production. Fu

SUBMITTER: Chowdhury-Paul S 

PROVIDER: S-EPMC10651043 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature