Exploring the secrets of super-aging: a UK Biobank study on brain health and cognitive function.

ABSTRACT: Communities across the globe are faced with a rapidly aging society, where age is the main risk factor for cognitive decline and development of Alzheimer's and related diseases. Despite extensive research, there have been no successful treatments yet. A rare group of individuals called "super-agers" have been noted to thrive with their exceptional ability to maintain a healthy brain and normal cognitive function even in old age. Studying their traits, lifestyles, and environments may provide valuable insight. This study used a data-driven approach to identify potential super-agers among 7121 UK Biobank participants and found that these individuals have the highest total brain volume, best cognitive performance, and lowest functional connectivity. The researchers suggest a novel hypothesis

SUBMITTER: Klinedinst BS 

PROVIDER: S-EPMC10651574 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature