Body mass index and waist circumference in relation to risk of recurrence and progression after non-muscle invasive bladder cancer.

ABSTRACT:

Background

Obesity may be associated with increased risk of recurrence and progression in patients with non-muscle invasive bladder cancer (NMIBC), but evidence is limited and inconsistent. We examined the associations of body mass index (BMI), waist circumference, and waist-to-hip ratio (WHR) with risk of recurrence and progression among patients with NMIBC.

Methods

This prospective study included 1029 patients diagnosed with primary NMIBC between 2014 and 2017. Patients reported weight 2 years before diagnosis at baseline, and weight, waist and hip circumference at 3 months postdiagnosis. Associations were quantified using Cox proportional hazard analyses, adjusted for clinical and lifestyle characteristics.

Results

More than half of patients were overweight (49%) o

SUBMITTER: van Zutphen M 

PROVIDER: S-EPMC10652337 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature