Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study.

ABSTRACT:

Background

Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited evidence for the effect of long-term elevation of AIP on ischemic stroke. Therefore, we aimed to characterize the relationship between cumulative exposure to AIP and the risk of ischemic stroke.

Methods

A total of 54,123 participants in the Kailuan Study who attended consecutive health examinations in 2006, 2008, and 2010 and had no history of ischemic stroke or cancer were included. The time-weighted cumulative AIP (cumAIP) was calculated as a weighted sum of the mean AIP values for each time interval and then normalized to the total duration of exposure (2006-2010). Participants were divided into four groups according to quartile of cumAIP: the

SUBMITTER: Zheng H 

PROVIDER: S-EPMC10652447 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature