Streptococcus strain D19^T as a probiotic candidate to modulate oral health.

ABSTRACT:

Background

As probiotics protect host cells, they are used to treat bacterial infections. It has been indicated that probiotics may prevent or reduce the attachment of pathogens to host cells. In this study, Streptococcus strain D19^T was isolated from the oropharynx of a healthy child, and its adhesion performance and Staphylococcus aureus adhesion inhibition effect were analysed using human bronchial epithelial (16-HBE) cells, as an in vitro cell model. We evaluated the probiotic properties of the D19^T strain based on its acid-base, bile salt, and lysozyme tolerance; antibacterial activity; cytotoxicity; antibiotic sensitivity; in vitro adhesion to 16-HBE cells; and competitive, exclusion, and displacement effects against S. aureus.

Results

Streptococc

SUBMITTER: Zhang WX 

PROVIDER: S-EPMC10652534 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature