Epidemiology and transmission of hepatitis A in Shaanxi (western China) after more than ten years of universal vaccination.

ABSTRACT:

Background

Hepatitis A (HepA) vaccination and economic factors can change the epidemiology of HepA. In China, the implementation of free vaccination for children under 1.5 years of age in 2008 has resulted in a decline in the overall incidence of HepA. Nevertheless, further investigation is required to comprehensively understand the epidemiological patterns of HepA in economically disadvantaged regions of China.

Method

In this study, we evaluated the incidence, seroprevalence, and transmission characteristics of HepA in Shaanxi with less economically developed. We obtained data on reported cases of HepA from 2005 to 2020. Blood samples from 1,559 individuals aged 0 to 60 years were tested for anti-hepatitis A (HAV) antibodies. A questionnaire survey and blood sample collecti

SUBMITTER: Hu X 

PROVIDER: S-EPMC10652842 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature