Strong association of lumbar disk herniation with diabetes mellitus: a 12-year nationwide retrospective cohort study.

ABSTRACT:

Background

Despite reports on the association between diabetes mellitus (DM) and lumbar disk herniation (LDH), large-scale, nationwide studies exploring this relationship are lacking. We aimed to examine the profiles of DM in individuals with LDH and explore the potential mechanisms underlying the development of these disorders.

Methods

This retrospective, population-based study was conducted between 2008 and 2019 using data from the National Health Insurance (NHI) research database in Taiwan. The primary outcome was the date of initial LDH diagnosis, death, withdrawal from the NHI program, or end of the study period.

Results

In total, 2,662,930 individuals with and 16,922,546 individuals without DM were included in this study; 719,068 matched pairs were established f

SUBMITTER: Li JX 

PROVIDER: S-EPMC10652879 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature