Phylogeny, Ecology, and Gene Families Covariation Shaped the Olfactory Subgenome of Rodents.

ABSTRACT: Olfactory receptor (OR) genes represent the largest multigenic family in mammalian genomes and encode proteins that bind environmental odorant molecules. The OR repertoire is extremely variable among species and is subject to many gene duplications and losses, which have been linked to ecological adaptations in mammals. Although they have been studied on a broad taxonomic scale (i.e., placental), finer sampling has rarely been explored in order to better capture the mechanisms that drove the evolution of the OR repertoire. Among placental mammals, rodents are well-suited for this task, as they exhibit diverse life history traits, and genomic data are available for most major families and a diverse array of lifestyles. In this study, 53 rodent published genomes were mined for their OR subge

SUBMITTER: Courcelle M 

PROVIDER: S-EPMC10653590 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature