Association of acute kidney injury with the risk of cognitive impairment or dementia: a systematic review and meta-analysis.

ABSTRACT:

Purpose

Since previous studies have shown a paradoxical relationship between acute kidney injury (AKI) and risk of cognitive impairment, there is an urgent need for a meta-analysis to assess the relationship between AKI and risk of cognitive impairment or dementia.

Materials and methods

From database inception to October 2023, we searched PubMed, OVID (Medline), Embase, Web of Science, and Cochrane Library. This study examined AKI and cognitive impairment or dementia observational studies. Two authors independently assessed cohort and cross-sectional study quality using the Newcastle-Ottawa Scale and AHRQ Scale. They also used ROBINS-I to assess bias. The meta-analysis used fixed effects. Sensitivity analysis verified results stability. The funnel plot, Egger test, and Begg

SUBMITTER: Wang J 

PROVIDER: S-EPMC10653765 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature