PhcX Is a LqsR-family response regulator that contributes to <i>Ralstonia solanacearum</i> virulence and regulates multiple virulence factors.

ABSTRACT:

Importance

The bacterial wilt caused by the soil-borne phytopathogen Ralstonia solanacearum is one of the most destructive crop diseases. To achieve a successful infection, R. solanacearum has evolved an intricate regulatory network to orchestrate the expression of an arsenal of virulence factors and fine-tune the allocation of energy. However, despite the wealth of knowledge gained in the past decades, many players and connections are still missing from the network. The importance of our study lies in the identification of PhcX, a novel conserved global regulator with critical roles in modulating the virulence and metabolism of R. solanacearum. PhcX affects many well-characterized regulators and exhibits contrasting modes of regulation from the central regulat

SUBMITTER: Liu Q 

PROVIDER: S-EPMC10653808 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature