Low-density hepatitis C virus infectious particles are protected from oxidation by secreted cellular proteins.

ABSTRACT:

Importance

Assessments of viral stability on surfaces or in body fluids under different environmental conditions and/or temperatures are often performed, as they are key to understanding the routes and parameters of viral transmission and to providing clues on the epidemiology of infections. However, for most viruses, the mechanisms of inactivation vs stability of viral particles remain poorly defined. Although they are structurally diverse, with different compositions, sizes, and shapes, enveloped viruses are generally less stable than non-enveloped viruses, pointing out the role of envelopes themselves in virus lability. In this report, we investigated the properties of hepatitis C virus (HCV) particles with regards to their stability. We found that, compared to alternative envel

SUBMITTER: Granier C 

PROVIDER: S-EPMC10653866 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature