Biological hydrogen cyanide emission globally impacts the physiology of both HCN-emitting and HCN-perceiving <i>Pseudomonas</i>.

ABSTRACT:

Importance

Bacteria communicate by exchanging chemical signals, some of which are volatile and can remotely reach other organisms. HCN was one of the first volatiles discovered to severely impact exposed organisms by inhibiting their respiration. Using HCN-deficient mutants in two Pseudomonas strains, we demonstrate that HCN's impact goes beyond the sole inhibition of respiration and affects both emitting and receiving bacteria in a global way, modulating their motility, biofilm formation, and production of antimicrobial compounds. Our data suggest that bacteria could use HCN not only to control their own cellular functions, but also to remotely influence the behavior of other bacteria sharing the same environment. Since HCN emission occurs in both clinically and environment

SUBMITTER: Anand A 

PROVIDER: S-EPMC10653877 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature