Vesicle-enriched secretomes alter bacterial competitive abilities and are drivers of evolution in microbial communities.

ABSTRACT: Microbial membrane vesicles can carry compounds that inhibit bacterial growth, but how they impact the fitness of the vesicle-producing bacterial species and influence community dynamics remain unexplored questions. To address these questions, we examined the effect of vesicle-enriched secretomes (VESs) in different single-species and multi-species systems. Effects of VESs on single-species growth dynamics were determined for nine bacterial species belonging to four genera (Escherichia, Salmonella, Pseudomonas and Bacillus) in nutrient-rich and poor growth media. Results showed both species-specific and nutrient-dependent effects of the VESs on bacterial growth. The strongest antagonistic effects were observed for VES isolated from the natural isolates of E. coli, while those isolated from

SUBMITTER: Warsi OM 

PROVIDER: S-EPMC10653989 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature