Dataset Information
The timing of transcription of RpoS-dependent genes varies across multiple stresses in Escherichia coli K-12.
Ontology highlight
ABSTRACT: Importance
Bacteria adapt to changing environments by altering the transcription of their genes. Specific proteins can regulate these changes. This study explored how a single protein called RpoS controls how many genes change expression during adaptation to three stresses. We found that: (i) RpoS is responsible for activating different genes in different stresses; (ii) that during a stress, the timing of gene activation depends on the what stress it is; and (iii) that how much RpoS a gene needs in order to be activated can predict when that gene will be activated during the stress of stationary phase.
SUBMITTER: Adams J
PROVIDER: S-EPMC10654073 | biostudies-literature | 2023 Oct
REPOSITORIES: biostudies-literature
Publications
The timing of transcription of RpoS-dependent genes varies across multiple stresses in <i>Escherichia coli</i> K-12.
mSystems 20230825 5
<h4>Importance</h4>Bacteria adapt to changing environments by altering the transcription of their genes. Specific proteins can regulate these changes. This study explored how a single protein called RpoS controls how many genes change expression during adaptation to three stresses. We found that: (i) RpoS is responsible for activating different genes in different stresses; (ii) that during a stress, the timing of gene activation depends on the what stress it is; and (iii) that how much RpoS a ge ...[more]
