Epidemiological characteristics of multidrug-resistant Acinetobacter baumannii ST369 in Anhui, China.

ABSTRACT: Acinetobacter baumannii is of growing concern for global health owing to its ability to evade the immune system and develop resistance to antibiotics. We analyzed A. baumannii using the National Center for Biotechnology Information (https://www.ncbi.nlm.nih.gov/pathogens) database and observed that the ST369 strain isolated in China constituted over 50% of the globally prevalent ST369 clones. This finding highlights the significant impact of ST369 on public health in China. In this study, we examined eight strains of multidrug-resistant A. baumannii ST369 isolated from a provincial hospital in China. We conducted whole-genome sequencing, comparative genomic analysis, and phenotypic experiments, and used the Galleria mellonella infection model to achieve a compre

SUBMITTER: Huang Y 

PROVIDER: S-EPMC10654100 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature