The association between constipation and subsequent risk of atopic dermatitis in children: the Japan Environment and Children's Study.

ABSTRACT:

Background

No study has examined the association between constipation and atopic dermatitis (AD) in infants and toddlers. We aimed to explore that association in toddlers using the data from a nationwide birth cohort study.

Methods

From the Japan Environment and Children's Study, a nationwide prospective birth cohort study that began in 2011, children born in a singleton live birth were analyzed. Participants completed questionnaires containing questions related to bowel movements and AD, during 1.5 to 3 years after birth. Constipation at 1 year of age was defined as having ≤2 bowel movements per week. AD was defined based on participant's responses to the modified ISAAC questionnaire and/or self-reported physician's diagnosis. Outcome was defined as the cumulative number of

SUBMITTER: Takano Y 

PROVIDER: S-EPMC10654214 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature