Diarrheal woes in transplantation from real world settings with special focus on clostridium difficile infection.

ABSTRACT:

Background

Diarrhea is the major cause of discomfort and morbidity of patients undergoing hematopoietic stem cell transplant (HSCT). The cause of diarrhea may be infective or non-infective.

Methods

This is a prospective single center observational study from North India conducted over a period of approximately 4 years among 105 patients who underwent HSCT (autologous-72, allogeneic-33). The objective of the study was to identify the overall incidence and characteristics of diarrhea in HSCT in the real world, to evaluate any differences among allogeneic or autologous transplants, incidence of C Difficile among diarrheal patients, and antimicrobial usage among these patients.

Results

Diarrhea was present in 89 of 105 patients (84.7%). The mean diarrheal duration was of

SUBMITTER: Yanamandra U 

PROVIDER: S-EPMC10654365 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature