Racial, Ethnic, and Gender Diversity in United States Ophthalmology Clinical Trials.

ABSTRACT:

Purpose

To investigate the representation of various gender, racial, and ethnic groups in ophthalmology clinical trials conducted in the United States (US) between 1997 and 2022.

Design

Retrospective cross-sectional study.

Participants

We included all participants in completed phase II/III, III, and IV ophthalmology clinical trials reported on the ClincialTrials.gov database.

Methods

The proportional enrollment of each racial/ethnic and gender group in the clinical trials was calculated and compared with the US population. We also investigated the impact of various clinical trial features on the rate of reporting demographic information and enrollment of minorities.

Main outcome measures

Proportional enrollment of each gender and race/ethnicity group com

SUBMITTER: Montazeri F 

PROVIDER: S-EPMC10654370 | biostudies-literature | 2024 Jan-Feb

REPOSITORIES: biostudies-literature