Markers of inflammation predict survival in newly diagnosed cirrhosis: a prospective registry study.

ABSTRACT: The inflammatory activity in cirrhosis is often pronounced and related to episodes of decompensation. Systemic markers of inflammation may contain prognostic information, and we investigated their possible correlation with admissions and mortality among patients with newly diagnosed liver cirrhosis. We collected plasma samples from 149 patients with newly diagnosed (within the past 6 months) cirrhosis, and registered deaths and hospital admissions within 180 days. Ninety-two inflammatory markers were quantified and correlated with clinical variables, mortality, and admissions. Prediction models were calculated by logistic regression. We compared the disease courses of our cohort with a validation cohort of 86 patients with cirrhosis. Twenty of 92 markers of inflammation correlated signific

SUBMITTER: Mynster Kronborg T 

PROVIDER: S-EPMC10654496 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature