Heart rate recovery after orthostatic challenge and cardiopulmonary exercise testing in older individuals: prospective multicentre observational cohort study.

ABSTRACT:

Background

Impaired vagal function in older individuals, quantified by the 'gold standard' delayed heart rate recovery after maximal exercise (HRR^exercise), is an independent predictor of cardiorespiratory capacity and mortality (particularly when HRR ≤12 beats min^-1). Heart rate also often declines after orthostatic challenge (HRR^orthostatic), but the mechanism remains unclear. We tested whether HRR^orthostatic reflects similar vagal autonomic characteristics as HRR^exercise.

Methods

Prospective multicentre cohort study of subjects scheduled for cardiopulmonary exercise testing (CPET) as part of routine care. Before undergoing CPET, heart rate was measured with participants seated for 3 min, before standing for 3 min (HRR

SUBMITTER: James A 

PROVIDER: S-EPMC10654531 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature