Renal complications in chronic hypoparathyroidism - a systematic cross-sectional assessment.

ABSTRACT:

Context

Although renal long-term complications are acknowledged in chronic hypoparathyroidism (HPT), standardized investigations are scarce.

Objective

To systematically investigate renal complications and their predictors in hypoparathyroid patients compared to matched individuals.

Design

Prospective observational study in 161 patients with chronic HPT.

Methods

Patients received renal ultrasound, clinical and laboratory assessments. An individual 1:3 matching with participants from the German population-based Study of Health in Pomerania was performed.

Results

Of 161 patients (92% postoperative HPT), prevalence of eGFR <60ml/min/1.73m² was 21%, hypercalciuria 41%. Compared to healthy individuals, HPT patients had a significantly lower eGFR (74

SUBMITTER: Gronemeyer K 

PROVIDER: S-EPMC10654620 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature