Evaluation of behavioural selection processes in conflict scenarios using a newly developed mouse behavioural paradigm.

ABSTRACT: Selecting an appropriate behaviour is critical for survival in conflict scenarios, wherein animals face both appetitive and aversive stimuli. Behavioural selection consists of multiple processes: (1) animals remain quiet in a safe place to avoid aversive stimuli (suspension), (2) once they decide to take risks to approach appetitive stimuli, they assess the risks (risk assessment), and (3) they act to reach the reward. However, most studies have not addressed these distinct behavioural processes separately. Here, we developed a new experimental paradigm called the three-compartment conflict task to quantitatively evaluate conflict processes. Our apparatus consisted of start, flat, and grid compartments. Mice needed to explore the grid compartment, where they might receive foot shocks while

SUBMITTER: Miyagami Y 

PROVIDER: S-EPMC10654709 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature