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Predictors and Pathophysiology of Axial Postural Abnormalities in Parkinsonism: A Scoping Review.


ABSTRACT:

Background

Postural abnormalities involving the trunk are referred to as axial postural abnormalities and can be observed in over 20% of patients with Parkinson's disease (PD) and in atypical parkinsonism. These symptoms are highly disabling and frequently associated with back pain and a worse quality of life in PD. Despite their frequency, little is known about the pathophysiology of these symptoms and scant data are reported about their clinical predictors, making it difficult to prompt prevention strategies.

Objectives

We conducted a scoping literature review of clinical predictors and pathophysiology of axial postural abnormalities in patients with parkinsonism to identify key concepts, theories and evidence on this topic.

Methods

We applied a systematic approach

SUBMITTER: Artusi CA 

PROVIDER: S-EPMC10654876 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature