Fear of Missing Organisms (FOMO): the discordance among broad-spectrum empiric antibiotic therapy, microbiologic results, and definitive antibiotic therapy for diabetic foot infections and lower extremity osteomyelitis.

ABSTRACT:

Objective

Empiric broad-spectrum antibiotic therapy is commonly prescribed for patients hospitalized with diabetic foot infections (DFI) and lower extremity osteomyelitis (OM). The primary objective was to evaluate the concordance between empiric antibiotic therapy, microbiologic results, and definitive antibiotic therapy with a focus on methicillin-resistant Staphylococcus aureus (MRSA) and resistant gram-negative organisms. The secondary objective was to evaluate the negative predictive values (NPV) of select risk factors for MRSA and resistant gram-negative organisms for microbiologic results with these organisms.

Design

Retrospective cohort study.

Setting

Safety-net health system in Ohio.

Patients

Adults hospitalized and receiving antibiotic therapy

SUBMITTER: Morelli MK 

PROVIDER: S-EPMC10654958 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature