The incidence, impact, and risk factors for moderate to severe persistent pain after breast cancer surgery: a prospective cohort study.

ABSTRACT:

Background

Few Australasian studies have evaluated persistent pain after breast cancer surgery.

Objective

To evaluate the incidence, impact, and risk factors of moderate to severe persistent pain after breast cancer surgery in a New Zealand cohort.

Design

Prospective cohort study.

Methods

Consented patients were reviewed at 3 timepoints (preoperative, 2 weeks and 6 months postoperative). Pain incidence and interference, psychological distress and upper limb disability were assessed perioperatively. Clinical, demographic, psychological, cancer treatment-related variables, quantitative sensory testing, and patient genotype (COMT, OPRM1, GCH1, ESR1, and KCNJ6) were assessed as risk factors using multiple logistic regression.

Results

Of the 173 patients recr

SUBMITTER: Chiang DLC 

PROVIDER: S-EPMC10655209 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature